Course Syllabus
Monday, Wednesday, and most Fridays 11a:12:30p
This course aims to develop deep quantitative understanding of basic forces of evolution, molecular evolution, genetic variations and their dynamics in populations, genetics of complex phenotypes, and genome-wide association studies. Application of these foundational concepts to cutting edge studies in epigenetics, gene regulation and chromatin; cancer genomics, and microbiomes. Modules consist of lectures, journal club discussions of high impact publications, and guest lectures that provide clinical correlates. Homework assignments and final projects aim to develop hands-on experience and understanding of genomic data from evolutionary principles.
Teaching Staff
Professor Leonid Mirny; leonid@mit.edu
Professor Tami Lieberman; tami@mit.edu
Office Hours: Tu 4-5p or as requested; E25-551b and Zoom simultaneous
Course Assistant Erik Owen; eowen@mit.edu
Office Hours: Monday 12:30-1:30pm, 4-146
Homework and Grading
- 3 Problem Sets (15% each; 45%)
- Participation in Paper Discussions (20%)
- Lead 1 discussion
- Leave comments on all papers by 9p day before class)
- Final project (~5 pages) (35%)
- Preliminary
- Oral
- Written
Textbooks
John H. Gillespie's Population Genetics: A Concise Guide
CEE Communication Lab
The CEE Comm Lab offers one-on-one communication coaching for undergrads, grads, and postdocs. Whether you’re working on a scientific paper, proposal, presentation, or application, our team of trained CEE PhD and Postdoc Comm Fellows can provide useful feedback at any stage, from initial brainstorming to final polishing. As this course is affiliated with Course 1, you are welcome to use Comm Lab services and can schedule free in-person or Zoom appointments throughout the year. Since 2020, the Comm Lab has hosted more than 700 individual appointments with students and postdocs. To schedule an appointment please visit: mitcommlab.mit.edu/cee/
Course Summary:
| Date | Details | Due |
|---|---|---|